James G. Fox, DVM, MS, DACLAM, is a Professor and Director of the Division of Comparative Medicine and a Professor in the Division of Biological Engineering at the Massachusetts Institute of Technology. He is also an Adjunct Professor at Tufts University School of Veterinary Medicine and the University of Pennsylvania, School of Veterinary Medicine. He is a Diplomate and a past president of the American College of Laboratory Animal Medicine, past president of the Massachusetts Society of Medical Research, past chairman of AAALAC Council, and past chairman of the NCCR/NIH Comparative Medicine Study Section. He also is an elected fellow of the Infectious Disease Society of America and the American Gastroenterology Association. Professor Fox is the author of over 625 articles, 80 chapters, 3 patents and has edited and authored 15 texts in the field of in vivo model development and comparative medicine. He has served on the editorial board of several journals and is a past member of the NIH/NCRR Scientific Advisory Council. He has received numerous scientific awards including the AVMA’s Charles River Prize in Comparative Medicine, the AALAS Nathan Brewer Scientific Achievement Award, the AVMA Excellence in Research Award, the ACLAM Award for Scientific Achievement, the Pravin Bhatt award for research excellence and the AALAS Griffin Award. He has been studying infectious diseases of the gastrointestinal tract for the past 40 years and has focused on the pathogenesis of Campylobacter spp. and Helicobacter spp. infection in humans and animals. His laboratory developed the ferret as a model for both campylobacter and helicobacter associated disease as well as the first rodent model to study helicobacter associated gastric disease including gastric cancer. Dr. Fox is considered an international authority on the epidemiology and pathogenesis of enterohepatic helicobacters in humans and animals. He is largely responsible for identifying, naming, and describing many of the diseases attributed to various Helicobacter species; most notably their association with hepatitis, liver tumors, inflammatory bowel disease and colon cancer in mice. His laboratory most recently has described the pivotal role that Helicobacter spp. play in the development of the gallstones in mice fed a lithogenic diet; thus linking this finding to his earlier description of Helicobacter spp. associated chronic cholecystitis and gallstones in Chilean women, a population at high risk of developing gallbladder cancer. He also has had a long-standing interest in zoonotic diseases as well as biosafety issues associated with in vivo models. His past and current research has been funded by NIH and NCI, as well as by private industrial sources, for the past 40 years. He has been the principal investigator of an NIH postdoctoral training grant for veterinarians for the past 29 years. He consults nationally and internationally with government, academia and industry. In 2004 Professor Fox was elected to the National Academy of Medicine of the National Academy of Sciences.
Mark T. Whary, DVM, PhD, DACLAM, is the Associate Director and along with Dr. Fox is responsible for management of the MIT animal resource program. Dr. Whary is the principal veterinary reviewer of animal care and use protocols, is a primary contact for regulatory issues and oversees training of new investigators. Dr. Whary also serves on the Radiation Protection Committee, the Division’s environmental health and safety committee, manages the occupational health program, contributes to the postdoctoral program in comparative medicine for veterinarians and provides support for web page management and technical writing for the Division. Dr. Whary’s research in mucosal immunology has focused on the pathogenesis of helicobacter infections in humans and in genetically engineered mice as models of human infectious gastritis, hepatitis and inflammatory bowel disease. Dr. Whary manages a germfree and gnotobiotic mouse facility to focus on gut flora ecology and the onset of gastrointestinal and hepatic diseases in mouse models.
Susan Erdman, DVM, MPH, DACLAM, is an Assistant Director and Chief of Clinical Resources within the Division. She completed the postdoctoral training program in Comparative Medicine at MIT and received a Master’s degree from Harvard in 1992. She also serves as a PI or co-PI on several NIH and DOD supported grants. Her research focus is roles of inflammatory disease in cancer and the role of probiotics in promoting health. Along with Dr. Marini, she coordinates the training schedule and seminars for the postdoctoral trainees.
Robert P. Marini, DVM, DACLAM, Assistant Director, is a member of DCM’s clinical staff and is Chief of the Division’s clinical surgical facilities. Dr. Marini is responsible for coordinating and supervising all major survival surgery in non-rodent mammalian species. Dr. Marini’s interests focus on experimental surgery and anesthesiology. He actively collaborates on several NIH funded research projects as well as being involved in the investigation of spontaneously occurring diseases of laboratory animals. Dr. Marini is closely involved in didactic coursework involving physical and chemical animal restraint, specialized surgical procedures, anesthetic regimens, and basic life support measures employed in a wide variety of animal species. He coordinates the training schedule and seminars for the postdoctoral trainees. He also holds an appointment as a lecturer in the Harvard-MIT Division of Health Services and Technology.